Julian Downward
The Francis Crick Institute(GB)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, PI3K/AKT/mTOR signaling in cancer, Lung Cancer Treatments and Mutations, Cancer Immunotherapy and Biomarkers, Cancer-related Molecular Pathways
Most-Cited Works
- → Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing(2012)7,705 cited
- → Targeting RAS signalling pathways in cancer therapy(2003)3,218 cited
- → Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells(1984)2,767 cited
- → Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences(1984)2,530 cited
- → Phosphatidylinositol-3-OH kinase direct target of Ras(1994)1,929 cited
- → Mechanisms and consequences of activation of protein kinase B/Akt(1998)1,306 cited
- → Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB(1997)1,158 cited