Jeroen C. Verheijen

Publications by Year

Research Areas

PI3K/AKT/mTOR signaling in cancer, Advanced biosensing and bioanalysis techniques, DNA and Nucleic Acid Chemistry, Synthesis and biological activity, Protein Kinase Regulation and GTPase Signaling

Most-Cited Works

• → Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin(2009)326 cited
• → Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2(2010)208 cited
• → ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines(2009)98 cited
• → Morpholine Derivatives Greatly Enhance the Selectivity of Mammalian Target of Rapamycin (mTOR) Inhibitors(2009)97 cited
• → Transition Metal Derivatives of Peptide Nucleic Acid (PNA) OligomersSynthesis, Characterization, and DNA Binding(2000)85 cited
• → Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): Optimization of the 1-substituent(2010)63 cited
• → Efficient Hydrolysis of RNA by a PNA - Diethylenetriamine Adduct(2000)63 cited
• → Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases(2020)59 cited
• → Discovery of 4-Morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (mTOR): Optimization of the 6-Aryl Substituent(2009)53 cited
• → Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase(2009)51 cited