John F. Davis
Broad Institute(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Bioinformatics and Genomic Networks, Protein Degradation and Inhibitors, Advanced Proteomics Techniques and Applications, Gene expression and cancer classification
Most-Cited Works
- → A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles(2017)3,590 cited
- → A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations(2018)94 cited
- → Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines(2022)
- → Abstract 4228: PRISM cancer cell viability profiling enables insights into clinical candidate target selectivity: A case study revealing the most selective PRMT5 inhibitors for cancers with MTAP loss(2025)
- Stress Gene Expression in H. dujardini(2010)
- → Abstract 4025: Accelerating drug repurposing for cancer therapy using multiplexed viability assays(2017)
- → Abstract 2748: Identifying therapeutic mechanism of action and new potential patient populations using PRISM(2023)
- → Abstract A026: Defining the epigenetic drug landscape and rational combinations for pediatric cancer using the PRISM screening assay(2025)