Chao‐Yie Yang
University of Tennessee Health Science Center(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, ATP Synthase and ATPases Research
Most-Cited Works
- → The PDBbind Database: Methodologies and Updates(2005)924 cited
- → A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo(2019)589 cited
- → Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer(2019)377 cited
- → Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression(2017)356 cited
- → Targeting the MDM2–p53 Protein–Protein Interaction for New Cancer Therapy: Progress and Challenges(2017)312 cited
- → Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression(2018)295 cited