C.H. Arrowsmith
University Health Network(CA)University of Toronto(CA)Princess Margaret Cancer Centre(CA)Structural Genomics Consortium(CA)
Publications by Year
Research Areas
Enzyme Structure and Function, Epigenetics and DNA Methylation, Cancer-related gene regulation, Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways
Most-Cited Works
- → Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family(2012)1,724 cited
- → Epigenetic protein families: a new frontier for drug discovery(2012)1,294 cited
- → Consistent blind protein structure generation from NMR chemical shift data(2008)859 cited
- → The promise and peril of chemical probes(2015)841 cited
- → Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids(2015)739 cited
- → Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation(2010)595 cited