F. Thomas Boyle
AstraZeneca (United Kingdom)(GB)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Cancer-related Molecular Pathways, Biochemical and Molecular Research, DNA Repair Mechanisms, Carcinogens and Genotoxicity Assessment
Most-Cited Works
- → Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor(2002)212 cited
- → N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2(2004)122 cited
- → Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 withO6-Substituted Guanine Derivatives(2002)84 cited
- → Resistance-Modifying Agents. 8. Inhibition of O6-Alkylguanine-DNA Alkyltransferase by O6-Alkenyl-, O6-Cycloalkenyl-, and O6-(2-Oxoalkyl)guanines and Potentiation of Temozolomide Cytotoxicity in Vitro by O6-(1-Cyclopentenylmethyl)guanine(2000)49 cited
- → The Duration of the Inhibition of Thymidylate Synthase in Intact L1210 Cells Exposed to Two Different Classes of Quinazoline Analogues(1993)5 cited
- → The Reduced Folate/Methotrexate Carrier and a Membrane-Associated Folate Binding Protein as Transport Routes for Novel Antifolates: Structure-Activity Relationships(1993)4 cited