Jean‐François Truchon
Telesta Therapeutics (Canada)(CA)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Advanced Chemical Physics Studies, DNA and Nucleic Acid Chemistry, HIV/AIDS drug development and treatment, Protease and Inhibitor Mechanisms
Most-Cited Works
- → Evaluating Virtual Screening Methods: Good and Bad Metrics for the “Early Recognition” Problem(2007)843 cited
- → Comparison of Topological, Shape, and Docking Methods in Virtual Screening(2007)415 cited
- → A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds(2006)147 cited
- → Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses(2013)99 cited
- → Natural Products in Medicine: Transformational Outcome of Synthetic Chemistry(2014)93 cited
- → Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306(2022)65 cited
- → Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ(2022)62 cited
- → The identification of potent, selective, and bioavailable cathepsin S inhibitors(2007)58 cited
- → Solvation of formic acid and proton transfer in hydrated clusters(2002)54 cited
- → Intramolecular interaction energies in model alanine and glycine tetrapeptides. Evaluation of anisotropy, polarization, and correlation effects. A parallel ab initio HF/MP2, DFT, and polarizable molecular mechanics study(2004)36 cited