Christopher F. Claiborne
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Cancer Treatment and Pharmacology, Synthetic Organic Chemistry Methods, Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways
Most-Cited Works
- → An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer(2009)1,965 cited
- → Total synthesis of taxol(1994)1,085 cited
- → Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ(2010)459 cited
- → Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase(2007)413 cited
- → Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays(2011)300 cited
- → Total Synthesis of taxol. 2. Construction of A and C ring intermediates and initial attempts to construct the ABC ring system(1995)216 cited
- → Olefin Metathesis in Cyclic Ether Formation. Direct Conversion of Olefinic Esters to Cyclic Enol Ethers with Tebbe-Type Reagents(1996)198 cited
- → Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer(2021)197 cited
- → Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase(1999)196 cited
- → Total Synthesis of Taxol. 3. Formation of Taxol's ABC Ring Skeleton(1995)160 cited