Daniel E. Beck
Purdue University West Lafayette(US)
Publications by Year
Research Areas
Bioactive Compounds and Antitumor Agents, Cancer therapeutics and mechanisms, Protein Tyrosine Phosphatases, Alzheimer's disease research and treatments, Synthesis and biological activity
Most-Cited Works
- Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells.(1989)
- → Synthesis and Biological Evaluation of New Carbohydrate-Substituted Indenoisoquinoline Topoisomerase I Inhibitors and Improved Syntheses of the Experimental Anticancer Agents Indotecan (LMP400) and Indimitecan (LMP776)(2014)69 cited
- → Discovery of Potent Indenoisoquinoline Topoisomerase I Poisons Lacking the 3-Nitro Toxicophore(2015)48 cited
- → Investigation of the Structure–Activity Relationships of Aza-A-Ring Indenoisoquinoline Topoisomerase I Poisons(2016)47 cited
- → Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors(2018)41 cited
- → Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons(2016)29 cited
- → Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential(2013)26 cited
- → SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease(2023)10 cited
- → A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators to treat Alzheimer's disease(2023)3 cited
- → A Target Enablement Package for the Inhibition of SHIP1 as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease(2022)2 cited