Christopher Towler
University of Leeds(GB)
Publications by Year
Research Areas
Crystallization and Solubility Studies, Protein Tyrosine Phosphatases, X-ray Diffraction in Crystallography, Analytical Chemistry and Chromatography, Galectins and Cancer Biology
Most-Cited Works
- → Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor(2016)286 cited
- → Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer(2020)210 cited
- → Impact of Molecular Speciation on Crystal Nucleation in Polymorphic Systems: The Conundrum of γ Glycine and Molecular ‘Self Poisoning'(2004)194 cited
- → Crystallization in Polymorphic Systems: The Solution-Mediated Transformation of β to α Glycine(2002)160 cited
- → Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)(2018)131 cited
- → 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors(2019)86 cited
- → The Crystallization of Glycine Polymorphs from Emulsions, Microemulsions, and Lamellar Phases(2002)82 cited
- → Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors(2019)80 cited
- → An Investigation into the Influence of Counterion on the Properties of Some Amorphous Organic Salts(2008)35 cited
- → Impurity effects on the corrosion of aluminium(1975)34 cited