Heidi Ackerly Wallweber
Joint Center for Structural Genomics(US)
Publications by Year
Research Areas
Endoplasmic Reticulum Stress and Disease, Cancer Immunotherapy and Biomarkers, Cellular transport and secretion, Multiple Myeloma Research and Treatments, Complement system in diseases
Most-Cited Works
- → T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition(2017)1,623 cited
- → Disruption of IRE1α through its kinase domain attenuates multiple myeloma(2019)112 cited
- → Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action(2014)82 cited
- → Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands(2020)41 cited
- → A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma(2022)39 cited
- → T cell co-stimulatory receptor CD28 is a primary target for PD-1–mediated inhibition(2016)37 cited
- → Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors(2021)21 cited
- → Evaluation of Assay Technologies for the Identification of Protein–Peptide Interaction Antagonists(2007)17 cited
- → Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity(2020)10 cited
- → Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling(2025)8 cited