Guy M. Lenk
University of Michigan(US)Institute of Human Genetics(PL)
Publications by Year
Research Areas
Cellular transport and secretion, Calcium signaling and nucleotide metabolism, Autophagy in Disease and Therapy, Hereditary Neurological Disorders, Aortic aneurysm repair treatments
Most-Cited Works
- → The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm(2008)724 cited
- → A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis(2013)305 cited
- → In vivo, Pikfyve generates PI(3,5)P 2 , which serves as both a signaling lipid and the major precursor for PI5P(2012)233 cited
- → Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2(2009)200 cited
- → Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms(2007)179 cited
- → Altered Cardiac Electrophysiology and SUDEP in a Model of Dravet Syndrome(2013)162 cited
- → Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence(2018)154 cited
- → Yunis-Varón Syndrome Is Caused by Mutations in FIG4, Encoding a Phosphoinositide Phosphatase(2013)141 cited
- → Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome(2020)137 cited
- → Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4(2011)123 cited