Sourav Das
St. Jude Children's Research Hospital(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Drug Transport and Resistance Mechanisms, Cancer therapeutics and mechanisms, Computational Drug Discovery Methods
Most-Cited Works
- → Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux(2014)192 cited
- → Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs(2021)145 cited
- → Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators(2021)97 cited
- → Binding Affinity Prediction with Property-Encoded Shape Distribution Signatures(2010)64 cited
- → Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox(2017)59 cited
- → Structure–Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions(2016)57 cited
- → Rapid Comparison of Protein Binding Site Surfaces with Property Encoded Shape Distributions(2009)45 cited
- → Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines(2024)41 cited
- → Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer(2020)41 cited
- → ABCG2 requires a single aromatic amino acid to “clamp” substrates and inhibitors into the binding pocket(2020)40 cited