Kyle R. Leeman
Mirati Therapeutics (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Reactions, Analytical Chemistry and Chromatography, Chemical Synthesis and Analysis, Crystallization and Solubility Studies, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Aqueous Phosphoric Acid as a Mild Reagent for Deprotection of tert-Butyl Carbamates, Esters, and Ethers(2006)97 cited
- → Mild Decarboxylative Activation of Malonic Acid Derivatives by 1,1′-Carbonyldiimidazole(2011)72 cited
- → Mixture Component Prediction Using Iterative Optimization Technology (Calibration-Free/Minimum Approach)(2013)49 cited
- → Aqueous phosphoric acid as a mild reagent for deprotection of the t-butoxycarbonyl group(2003)39 cited
- → Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling(2016)38 cited
- → Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability(2016)32 cited
- → Development of a New Variant of the Migita Reaction for Carbon−Sulfur Bond Formation Used in the Manufacture of Tetrahydro-4-[3-[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl-2H-pyran-4-carboxamide(2008)27 cited
- → Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β-Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2H-Pyranone(2013)24 cited
- → Palbociclib Commercial Manufacturing Process Development. Part III. Deprotection Followed by Crystallization for API Particle Property Control(2016)19 cited
- → Development of the Commercial Route for the Manufacture of a 5-Lipoxygenase Inhibitor PF-04191834(2015)14 cited