Dilinie P. Fernando
Publications by Year
Research Areas
Catalytic C–H Functionalization Methods, Catalytic Cross-Coupling Reactions, Chemical Synthesis and Analysis, Receptor Mechanisms and Signaling, Pancreatic function and diabetes
Most-Cited Works
- → Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy(2016)115 cited
- → New Practical Synthesis of Indazoles via Condensation of o-Fluorobenzaldehydes and Their O-Methyloximes with Hydrazine(2006)107 cited
- → A General Method for the Synthesis of Unsymmetrically Substituted Ureas via Palladium-Catalyzed Amidation(2009)83 cited
- → Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose(2020)69 cited
- → Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate(2014)67 cited
- → Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases(2015)57 cited
- → Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting(2020)29 cited
- → Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor(2013)27 cited
- → Abstract 1262: BLU-701 is a highly potent, brain-penetrant and WT-sparing next-generation EGFR TKI for the treatment of sensitizing (ex19del, L858R) and C797S resistance mutations in metastatic NSCLC(2021)24 cited
- → Expedient Synthesis of α-Heteroaryl Piperidines Using a Pd-Catalyzed Suzuki Cross-Coupling–Reduction Sequence(2014)22 cited