Iyassu K. Sebhat

Publications by Year

Research Areas

Regulation of Appetite and Obesity, Biochemical Analysis and Sensing Techniques, Pancreatic function and diabetes, Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology

Most-Cited Works

• → Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy(2017)331 cited
• → A role for the melanocortin 4 receptor in sexual function(2002)299 cited
• → Design and Pharmacology of N-[(3R)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist(2002)190 cited
• → Synthesis of the Antitumor Alkaloid (+)-Pancratistatin Using the β-Azidonation Reaction via a Prochiral 4-Arylcyclohexanone Derivative(1998)87 cited
• → Activation of melanocortin MC4 receptors increases erectile activity in rats ex copula(2002)82 cited
• → Application of the β-azidonation reaction to the synthesis of the antitumor alkaloid (+)-pancratistatin(1998)67 cited
• → Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity(2010)65 cited
• → AMPK activators – potential therapeutics for metabolic and other diseases(2009)63 cited
• → Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase(2017)56 cited
• → Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis(2020)53 cited