Vito Guagnano
Publications by Year
Research Areas
Fibroblast Growth Factor Research, Synthetic Organic Chemistry Methods, Cancer-related Molecular Pathways, Epigenetics and DNA Methylation, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase(2011)487 cited
- → Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation(2013)463 cited
- → FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor(2012)360 cited
- → Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets(2012)146 cited
- → Rescue Screens with Secreted Proteins Reveal Compensatory Potential of Receptor Tyrosine Kinases in Driving Cancer Growth(2012)107 cited
- → Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument(2016)77 cited
- → Entry into a new class of protein kinase inhibitors by pseudo ring design(2008)67 cited
- → Synthesis and biological evaluation of highly potent analogues of epothilones B and D(2000)61 cited
- → Tandem Inter [4 + 2]/Intra [3 + 2] Cycloadditions of Nitroalkenes. 15. The Bridged Mode (α-Tether)(1997)59 cited
- → Fibroblast Growth Factor Receptors as Novel Therapeutic Targets in SNF5-Deleted Malignant Rhabdoid Tumors(2013)57 cited