Josh T. Pearson
Amgen (United States)(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Monoclonal and Polyclonal Antibodies Research, Drug Transport and Resistance Mechanisms, Protein purification and stability, CAR-T cell therapy research
Most-Cited Works
- → An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice(2020)129 cited
- → Intact mass analysis of monoclonal antibodies by capillary electrophoresis—Mass spectrometry(2015)77 cited
- → Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity(2020)75 cited
- → Surface Plasmon Resonance Analysis of Antifungal Azoles Binding to CYP3A4 with Kinetic Resolution of Multiple Binding Orientations(2006)68 cited
- → Differential Time-Dependent Inactivation of P450 3A4 and P450 3A5 by Raloxifene: A Key Role for C239 in Quenching Reactive Intermediates(2007)54 cited
- → Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements(2008)51 cited
- → Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction(2011)45 cited
- → In Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen Extract(2009)37 cited
- → In Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid Conjugates(2012)34 cited
- → Catalytic versus Inhibitory Promiscuity in Cytochrome P450s: Implications for Evolution of New Function(2011)29 cited