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Brian Struss | doi.page

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Brian Struss

Aptose Biosciences (United States)(US)

Research Areas

Cytokine Signaling Pathways and Interactions, Melanoma and MAPK Pathways, Quinazolinone synthesis and applications

Most-Cited Works

→ Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E(2011)58 cited