William Sinko
Publications by Year
Research Areas
Protein Structure and Dynamics, Computational Drug Discovery Methods, Biochemical and Molecular Research, Microbial Natural Products and Biosynthesis, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- → Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation(2014)455 cited
- → Exploring the role of receptor flexibility in structure-based drug discovery(2013)152 cited
- → Accounting for Receptor Flexibility and Enhanced Sampling Methods in Computer‐Aided Drug Design(2012)111 cited
- → Population Based Reweighting of Scaled Molecular Dynamics(2013)110 cited
- → Antibacterial drug leads targeting isoprenoid biosynthesis(2012)108 cited
- → Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data(2017)105 cited
- → Discovery of Small Molecule Inhibitors of the PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP) by Chemical and Virtual Screening(2010)78 cited
- → Undecaprenyl Diphosphate Synthase Inhibitors: Antibacterial Drug Leads(2014)51 cited
- → Applying Molecular Dynamics Simulations to Identify Rarely Sampled Ligand‐bound Conformational States of Undecaprenyl Pyrophosphate Synthase, an Antibacterial Target(2011)41 cited
- → w-REXAMD: A Hamiltonian Replica Exchange Approach to Improve Free Energy Calculations for Systems with Kinetically Trapped Conformations(2012)41 cited