Kurt Deshayes
Publications by Year
Research Areas
Cell death mechanisms and regulation, Monoclonal and Polyclonal Antibodies Research, Ubiquitin and proteasome pathways, NF-κB Signaling Pathways, Glycosylation and Glycoproteins Research
Most-Cited Works
- → IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis(2007)1,198 cited
- → Glyburide inhibits the Cryopyrin/Nalp3 inflammasome(2009)802 cited
- → c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation(2008)534 cited
- → Structure-guided design of a selective BCL-XL inhibitor(2013)370 cited
- → c‐IAP1 and UbcH5 promote K11‐linked polyubiquitination of RIP1 in TNF signalling(2010)337 cited
- → cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production(2010)334 cited
- → Discovery of a Potent and Selective BCL-X L Inhibitor with in Vivo Activity(2014)328 cited
- → Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family(2007)273 cited
- → Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)(2012)247 cited
- → Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination(2011)226 cited