Éric Therrien
Schrodinger (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Synthesis and Catalytic Reactions, Carbohydrate Chemistry and Synthesis, Synthetic Organic Chemistry Methods
Most-Cited Works
- → An allosteric mechanism for potent inhibition of human ATP-citrate lyase(2019)187 cited
- → Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors(2003)98 cited
- → N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)(2008)87 cited
- → Medicinal Chemistry Projects Requiring Imaginative Structure-Based Drug Design Methods(2016)76 cited
- → Structure-Based Design, Synthesis, and Memapsin 2 (BACE) Inhibitory Activity of Carbocyclic and Heterocyclic Peptidomimetics(2005)73 cited
- → Development of a Computational Tool to Rival Experts in the Prediction of Sites of Metabolism of Xenobiotics by P450s(2012)71 cited
- → A Method for Induced-Fit Docking, Scoring, and Ranking of Flexible Ligands. Application to Peptidic and Pseudopeptidic β-secretase (BACE 1) Inhibitors(2005)58 cited
- → Synthesis of Diversely Functionalized Indolizidinones and Related Bicyclic Lactams Using Intramolecular Grubbs Olefin Metathesis and Dieckmann Condensation(2003)56 cited
- → Virtual Screening and Computational Optimization for the Discovery of Covalent Prolyl Oligopeptidase Inhibitors with Activity in Human Cells(2012)56 cited
- → Integrating Medicinal Chemistry, Organic/Combinatorial Chemistry, and Computational Chemistry for the Discovery of Selective Estrogen Receptor Modulators with Forecaster, a Novel Platform for Drug Discovery(2011)55 cited