Holger Kuehne
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Fluorine in Organic Chemistry, Cancer therapeutics and mechanisms, Antibiotic Resistance in Bacteria, Microbial Natural Products and Biosynthesis, HIV/AIDS drug development and treatment
Most-Cited Works
- → Novel Inhibitors of DNA Gyrase: 3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening(2000)378 cited
- → Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds(2013)46 cited
- → Chemiluminescence response of whole blood and separated blood cells in cases of experimentally induced pancreatitis and MDTQ-DA—Trasylol—ascorbic acid therapy(1991)10 cited
- → ChemInform Abstract: SYNTHESIS AND NMR STUDIES OF 2‐FLUOROTRIPHENYLPHOSPHINES AND THEIR DERIVATIVES(1983)
- → Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative anti‐Androgen Cyoctol.(2004)
- → Orally available Factor7a inhibitor(2005)
- → ChemInform Abstract: Structural Analogues of the Antibiotic Moenomycin A with a D‐Glucose‐ Derived Unit F.(1994)
- → Abstract 5769: Target identification of T-cell activating immunomodulatory tetrahydrothiazepines: DGKα and DGKζ inhibitors(2024)