Susan Wong
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, PI3K/AKT/mTOR signaling in cancer, Drug-Induced Hepatotoxicity and Protection, Pharmacological Effects and Toxicity Studies
Most-Cited Works
- → GDC-0449—A potent inhibitor of the hedgehog pathway(2009)385 cited
- → Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)(2012)247 cited
- → Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer(2010)131 cited
- → Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors(2013)123 cited
- → A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6(2013)107 cited
- → Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model(2016)99 cited
- → Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor(2010)88 cited
- → Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo(2002)87 cited
- → Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton’s Tyrosine Kinase Inhibitor(2011)74 cited
- → A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834(2015)61 cited