Yasuhiro Koh
Kumamoto University(JP)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, HIV/AIDS Research and Interventions, Pneumocystis jirovecii pneumonia detection and treatment, Biochemical and Molecular Research
Most-Cited Works
- → Novel bis -Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro(2003)366 cited
- → Spirodiketopiperazine-Based CCR5 Inhibitor Which Preserves CC-Chemokine/CCR5 Interactions and Exerts Potent Activity against R5 Human Immunodeficiency Virus Type 1 In Vitro(2004)221 cited
- → Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation(2013)197 cited
- → Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors(2012)177 cited
- → Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance(2006)155 cited
- → Potent Inhibition of HIV-1 Replication by Novel Non-peptidyl Small Molecule Inhibitors of Protease Dimerization(2007)148 cited
- → Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration(2012)121 cited
- → Bis‐Tetrahydrofuran: a Privileged Ligand for Darunavir and a New Generation of HIV Protease Inhibitors That Combat Drug Resistance(2006)117 cited
- → Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2′-ligands(2006)106 cited
- → Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine(2007)102 cited