Hon C. Hui
Gilead Sciences (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Respiratory viral infections research, Blood Coagulation and Thrombosis Mechanisms, Viral gastroenteritis research and epidemiology
Most-Cited Works
- → Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys(2016)1,579 cited
- → Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses(2017)653 cited
- → GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses(2017)505 cited
- → Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode: Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa(2001)124 cited
- → Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study(2015)122 cited
- → Glutathione-S-transferase Activates Novel Alkylating Agents(1994)104 cited
- → Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131(2007)94 cited
- → Isoenzyme-specific glutathione-S-transferase inhibitors: design and synthesis(1994)92 cited
- → Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity: Potent and Selective Inhibitors of Urokinase-Type Plasminogen Activator(2001)86 cited
- → Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV(2021)81 cited