Laura Gianellini
Nerviano Medical Sciences(IT)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Heat shock proteins research, Computational Drug Discovery Methods, Cancer-related Molecular Pathways, Cancer Treatment and Pharmacology
Most-Cited Works
- → PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer(2007)240 cited
- → Inhibition of protein–protein interactions: The discovery of druglike β‐catenin inhibitors by combining virtual and biophysical screening(2006)179 cited
- → PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity(2006)161 cited
- → NMS-P937, an Orally Available, Specific Small-Molecule Polo-like Kinase 1 Inhibitor with Antitumor Activity in Solid and Hematologic Malignancies(2012)119 cited
- Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo.(2010)
- → 4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors(2010)30 cited
- → NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases(2013)26 cited
- → Identification of Myb-binding Protein 1A (MYBBP1A) as a Novel Substrate for Aurora B Kinase(2010)26 cited
- → 5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors(2011)17 cited
- → Abstract 1615: NMS-812, a novel potent PERK inhibitor that also inhibits GCN2, exhibits strong anti-tumor activity as single agent and in combination in preclinical models(2023)4 cited