Giuseppe Cocconcelli
Siena Biotech (Italy)(IT)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Nicotinic Acetylcholine Receptors Study, Cholinesterase and Neurodegenerative Diseases, Synthesis and Biological Evaluation, Synthesis and Reactions of Organic Compounds
Most-Cited Works
- → A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks(2007)61 cited
- → Aryl azoles with neuroprotective activity—Parallel synthesis and attempts at target identification(2007)45 cited
- → Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)(2010)30 cited
- → Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series(2005)28 cited
- → Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)(2012)26 cited
- → 2,4(5)-Diarylimidazoles as inhibitors of hNaV1.2 sodium channels: Pharmacological evaluation and structure–property relationships(2009)26 cited
- → 2,4(5)-Diarylimidazoles: Synthesis and biological evaluation of a new class of sodium channel blockers against hNav1.2(2008)19 cited
- → N-[5-(5-Fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A Medicinal Chemistry Effort toward an α7 Nicotinic Acetylcholine Receptor Agonist Preclinical Candidate(2012)14 cited
- → Synthesis of Novel 4-Fluoro-2H-pyrazol-3-ylamines(2010)9 cited
- → A Practical Synthesis of 2,4(5)‐Diarylimidazoles from Simple Building Blocks.(2007)1 cited