JoAnn La Fargue
Roche (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Synthesis and biological activity, Melanoma and MAPK Pathways, Chronic Kidney Disease and Diabetes, Renal cell carcinoma treatment
Most-Cited Works
- → Pharmacokinetics and Safety of Sunitinib Malate in Subjects With Impaired Renal Function(2009)75 cited
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase(2006)64 cited