Rosemary A. Melarange

Publications by Year

Research Areas

Neuroscience and Neuropharmacology Research, Amino Acid Enzymes and Metabolism, Organic Chemistry Cycloaddition Reactions, Nitric Oxide and Endothelin Effects, Synthesis and biological activity

Most-Cited Works

• → Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators(2010)66 cited
• → Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia(2007)60 cited
• → Discovery ofN-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator(2010)47 cited
• → .beta.1-Selective adrenoceptor antagonists. 3. 4-Azolyl linked phenoxypropanolamines(1984)28 cited
• → .beta.1-Selective adrenoceptor antagonists. 2. 4-Ether-linked phenoxypropanolamines(1983)19 cited
• → ChemInform Abstract: β1‐SELECTIVE ADRENOCEPTOR ANTAGONISTS. 3. 4‐AZOLYL LINKED PHENOXYPROPANOLAMINES(1984)1 cited
• → Crystal structure of N-((2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H- inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human GluA2 receptor(2010)
• → Crystal structure of N,N-dimethyl-4-(3-(trifluoromethyl)-4,5,6,7- tetrahydro-1H-indazol-1-yl)benzamide in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 2.2A resolution.(2010)
• → Crystal structure of 1-(4-(1-pyrrolidinylcarbonyl)phenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 2.2A resolution.(2010)
• → ChemInform Abstract: β1‐SELECTIVE ADRENOCEPTOR ANTAGONISTS. 2. 4‐ETHER‐LINKED PHENOXYPROPANOLAMINES(1984)