Denise Grimm
Bristol-Myers Squibb (Germany)(DE)Bristol-Myers Squibb (United States)(US)University Medical Center Hamburg-Eppendorf(DE)Klinik und Poliklinik für Neurologie(DE)
Publications by Year
Research Areas
Peroxisome Proliferator-Activated Receptors, Cholesterol and Lipid Metabolism, Drug Transport and Resistance Mechanisms, Adipose Tissue and Metabolism, Diabetes, Cardiovascular Risks, and Lipoproteins
Most-Cited Works
- → Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils(2016)158 cited
- → Pharmacological Characterization of a Novel Liver X Receptor Agonist with Partial LXRα Activity and a Favorable Window in Nonhuman Primates(2014)40 cited
- → Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)(2010)40 cited
- → Novel Peroxisome Proliferator-Activated Receptor α Agonists Lower Low-Density Lipoprotein and Triglycerides, Raise High-Density Lipoprotein, and Synergistically Increase Cholesterol Excretion with a Liver X Receptor Agonist(2008)35 cited
- → Discovery of Highly Potent Liver X Receptor β Agonists(2016)33 cited
- → Synthesis and structure–activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARα selective activators- PPARα and PPARγ selectivity modulation