Tom D. Heightman
AstraZeneca (Brazil)(BR)AstraZeneca (Poland)(PL)Molecular Oncology (United States)(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Histone Deacetylase Inhibitors Research, Melanoma and MAPK Pathways, Epigenetics and DNA Methylation, Synthesis and biological activity
Most-Cited Works
- → Selective inhibition of BET bromodomains(2010)4,233 cited
- → Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases(1999)539 cited
- → Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras(2016)388 cited
- → BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones(2014)311 cited
- → Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery(2016)297 cited
- → A Structural View of the Action ofEscherichia coli(lacZ) β-Galactosidase,(2001)228 cited