Nicholas Huby
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Cancer Mechanisms and Therapy, Cyclopropane Reaction Mechanisms, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → .alpha.-Hydroxy esters as chiral auxiliaries in asymmetric cyclopropanations by rhodium(II)-stabilized vinylcarbenoids(1993)130 cited
- → Enantioselective Synthesis of Functionalized Tropanes by Rhodium(II) Carboxylate-Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Pyrroles(1997)112 cited
- → Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by HLA-DR Class II MHC Molecules. Design, Structure−Activity Relationships, and X-ray Crystal Structures(2000)91 cited
- → Synthesis of 2.beta.-Acyl-3.beta.-aryl-8-azabicyclo[3.2.1]octanes and Their Binding Affinities at Dopamine and Serotonin Transport Sites in Rat Striatum and Frontal Cortex(1994)82 cited
- → Homoanatoxin: A potent analogue of anatoxin-a(1992)79 cited
- → Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules(1999)58 cited
- → Enantioselective synthesis of tropanes by reaction of rhodium-stabilized vinylcarbenoids with pyrroles(1992)47 cited
- → Diastereoselectivity Enhancement in Cyclopropanation and Cyclopropenation Reactions of Chiral Diazoacetate Esters Catalyzed by Chiral Dirhodium(II) Carboxamides(1993)37 cited
- → Characterization of a Novel Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor with a Unique Mechanism of Action for Cancer Therapy(2009)32 cited
- → Preclinical In vivo Evaluation of Efficacy, Pharmacokinetics, and Pharmacodynamics of a Novel MEK1/2 Kinase Inhibitor RO5068760 in Multiple Tumor Models(2010)28 cited