S. Pazhanisamy
Vertex Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
HIV Research and Treatment, HIV/AIDS drug development and treatment, Click Chemistry and Applications, Melanoma and MAPK Pathways, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase(1997)275 cited
- → In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease(1995)186 cited
- → A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase(1998)135 cited
- → In Vitro and In Vivo Isotope Effects with Hepatitis C Protease Inhibitors: Enhanced Plasma Exposure of Deuterated Telaprevir versus Telaprevir in Rats(2009)97 cited
- → The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor(2011)83 cited
- → Kinetic Characterization of Human Immunodeficiency Virus Type-1 Protease-resistant Variants(1996)78 cited
- → Weak Binding of VX-478 to Human Plasma Proteins and Implications for Anti-Human Immunodeficiency Virus Therapy(1995)69 cited
- → Kinetic Mechanism of the p38-α MAP Kinase: Phosphoryl Transfer to Synthetic Peptides(2000)54 cited
- → Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors(2009)45 cited
- → Design and synthesis of novel conformationally restricted HIV protease inhibitors(1998)37 cited