Vasanthi S. Viswanathan
Broad Institute(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Cancer, Hypoxia, and Metabolism, Computational Drug Discovery Methods, Ferroptosis and cancer prognosis, Cancer Genomics and Diagnostics
Most-Cited Works
- → Regulation of Ferroptotic Cancer Cell Death by GPX4(2014)7,212 cited
- → Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway(2017)1,941 cited
- → Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition(2017)1,673 cited
- → A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis(2019)846 cited
- → Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles(2020)457 cited
- → An expanded universe of cancer targets(2021)217 cited
- → Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently(2019)119 cited
- → Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers(2020)112 cited
- → Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162(2021)107 cited
- → DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets(2016)68 cited