C. Brassington
Publications by Year
Research Areas
Eicosanoids and Hypertension Pharmacology, Colorectal Cancer Treatments and Studies, Melanoma and MAPK Pathways, Synthesis and Characterization of Heterocyclic Compounds, Drug-Induced Hepatotoxicity and Protection
Most-Cited Works
- → Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation(2012)169 cited
- → Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation(2015)118 cited
- → Structural basis of Lewis b antigen binding by the Helicobacter pylori adhesin BabA(2015)84 cited
- → Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives(2012)56 cited
- → Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis(2015)47 cited
- → Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors(2008)30 cited
- → From fragments to leads: novel bacterial NAD + -dependent DNA ligase inhibitors(2014)9 cited
- → Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor(2009)
- → Supplementary Materials and Methods, Supplementary Figures 1 through 8, and Supplementary Tables 1 through 6 from Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis(2023)
- → Fragment bound to H.influenza NAD dependent DNA ligase(2014)