Andrei V. Krivtsov
Boston Children's Hospital(US)Dana-Farber Cancer Institute(US)
Publications by Year
Research Areas
Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, Cancer-related gene regulation, Histone Deacetylase Inhibitors Research
Most-Cited Works
- → Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9(2006)1,517 cited
- → MLL translocations, histone modifications and leukaemia stem-cell development(2007)1,251 cited
- → MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L(2011)888 cited
- → The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML(2010)748 cited
- → H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias(2008)548 cited
- → The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia(2018)450 cited
- → A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia