Thomas B. Ladd
University of Florida(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Cholinesterase and Neurodegenerative Diseases, Drug Transport and Resistance Mechanisms, Neuroinflammation and Neurodegeneration Mechanisms
Most-Cited Works
- → Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production(2005)280 cited
- → Substrate-targeting γ-secretase modulators(2008)277 cited
- → High‐affinity interactions and signal transduction between Aβ oligomers and TREM 2(2018)171 cited
- → Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains(2012)110 cited
- → TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease(2018)103 cited
- → Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates(2006)94 cited
- → Short Aβ peptides attenuate Aβ42 toxicity in vivo(2017)86 cited
- → Signal Peptide Peptidase Forms a Homodimer That Is Labeled by an Active Site-directed γ-Secretase Inhibitor(2004)82 cited
- → Independent Generation of Aβ42 and Aβ38 Peptide Species by γ-Secretase(2008)75 cited
- → Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length(2011)67 cited