David B. Darr
University of North Carolina at Chapel Hill(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Computational Drug Discovery Methods, Nanoparticle-Based Drug Delivery, CAR-T cell therapy research, Advanced Breast Cancer Therapies
Most-Cited Works
- → Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer(2012)734 cited
- → Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model(2013)405 cited
- → Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling(2015)315 cited
- → Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy(2012)249 cited
- → A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer(2018)245 cited
- → Mutation-Specific RAS Oncogenicity Explains NRAS Codon 61 Selection in Melanoma(2014)217 cited
- → Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells(2011)203 cited
- → Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy(2020)189 cited
- → A high capacity polymeric micelle of paclitaxel: Implication of high dose drug therapy to safety and in vivo anti-cancer activity(2016)189 cited
- → Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex(2017)182 cited