Carson C. Thoreen
Yale University(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, RNA and protein synthesis mechanisms, Hippo pathway signaling and YAP/TAZ, RNA Research and Splicing, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1(2008)2,742 cited
- → An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1(2009)1,792 cited
- → Evaluation of Multidimensional Chromatography Coupled with Tandem Mass Spectrometry (LC/LC−MS/MS) for Large-Scale Protein Analysis: The Yeast Proteome(2002)1,677 cited
- → A proteomics approach to understanding protein ubiquitination(2003)1,607 cited
- → A unifying model for mTORC1-mediated regulation of mRNA translation(2012)1,472 cited
- → Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1(2006)1,398 cited
- → PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase(2007)1,204 cited
- → DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival(2009)1,182 cited
- → mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s(2006)681 cited
- → Integration of cytogenetic landmarks into the draft sequence of the human genome(2001)324 cited