David Riddell
North Shore Hospital(NZ)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Cholinesterase and Neurodegenerative Diseases, Drug Transport and Resistance Mechanisms, Cholesterol and Lipid Metabolism
Most-Cited Works
- → ApoE Promotes the Proteolytic Degradation of Aβ(2008)858 cited
- → Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor(2012)421 cited
- → Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels(2008)344 cited
- → Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts(2001)301 cited
- → The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease(2007)248 cited
- → Apolipoprotein E Inhibits Platelet Aggregation through the L-Arginine:Nitric Oxide Pathway(1997)209 cited
- → Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease(2009)157 cited
- → Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade(2008)140 cited
- → Nitric Oxide and Platelet Aggregation(1997)139 cited
- → Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies(2011)130 cited