David J. Madar

Publications by Year

Research Areas

Diabetes Treatment and Management, Peptidase Inhibition and Analysis, Neuropeptides and Animal Physiology, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods

Most-Cited Works

• → A Convergent Synthetic Route to (+)-Dynemicin A and Analogs of Wide Structural Variability(1997)208 cited
• → Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity(2015)150 cited
• → 3,5-Bis(trifluoromethyl)pyrazoles: A Novel Class of NFAT Transcription Factor Regulator(2000)120 cited
• → Potential Drug Targets and Progress Towards Pharmacologic Inhibition of Hepatic Glucose Production(2003)87 cited
• → Synthesis of (+)-dynemicin A and analogs of wide structural variability: establishment of the absolute configuration of natural dynemicin A(1995)83 cited
• → Discovery, Structure−Activity Relationship, and Pharmacological Evaluation of (5-Substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as Potent Dipeptidyl Peptidase IV Inhibitors(2006)61 cited
• → Discovery of ((4R,5S)-5-Amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a Highly Potent, Selective, Orally Efficacious, and Safe Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes(2006)52 cited
• → Prospects for Pharmacologic Inhibition of Hepatic Glucose Production(2003)51 cited
• → Total Synthesis of (+)-Damavaricin D(1997)50 cited
• → Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721(2001)48 cited