E. Allen Sickmier
Accent Therapeutics (United States)(US)
Publications by Year
Research Areas
Science, Research, and Medicine, RNA and protein synthesis mechanisms, RNA Research and Splicing, Biotechnology and Related Fields, Steroid Chemistry and Biochemistry
Most-Cited Works
- → Structural Basis for Polypyrimidine Tract Recognition by the Essential Pre-mRNA Splicing Factor U2AF65(2006)190 cited
- → Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes(2012)163 cited
- → From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)(2011)136 cited
- → Structural Basis for Apelin Control of the Human Apelin Receptor(2017)131 cited
- → X-Ray Structure of a Rex-Family Repressor/NADH Complex Insights into the Mechanism of Redox Sensing(2005)85 cited
- → Fragment-Linking Approach Using 19 F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase(2016)72 cited
- → The Panitumumab EGFR Complex Reveals a Binding Mechanism That Overcomes Cetuximab Induced Resistance(2016)72 cited
- → Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid(2012)64 cited
- → Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase(2016)64 cited
- → Polyethylene Glycol Modified FGF21 Engineered to Maximize Potency and Minimize Vacuole Formation(2013)61 cited