Joerg Weiske
Nuvisan (Germany)(DE)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Multiple Myeloma Research and Treatments, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction(2019)365 cited
- → Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action(2017)90 cited
- → Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer(2021)87 cited
- → Nuclear Translocation Uncovers the Amyloid Peptide Aβ42 as a Regulator of Gene Transcription*(2014)74 cited
- → Identification of Small Molecules that Modulate Mutant p53 Condensation(2020)57 cited
- → Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2-d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5(2018)41 cited
- → Cell-Based Protein Stabilization Assays for the Detection of Interactions between Small-Molecule Inhibitors and BRD4(2014)31 cited
- → Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening(2021)25 cited
- → Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling(2024)9 cited
- → Abstract 1771: BAY 1834942 is an immunotherapeutic antibody blocking the novel immune checkpoint regulator CEACAM6 (CD66c)(2018)3 cited