Mengchen Lu
Soochow University(CN)Suzhou Research Institute(CN)
Publications by Year
Research Areas
Genomics, phytochemicals, and oxidative stress, Glutathione Transferases and Polymorphisms, Advanced Chemical Sensor Technologies, Computational Drug Discovery Methods, Ubiquitin and proteasome pathways
Most-Cited Works
- → The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update(2016)766 cited
- → Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway(2018)281 cited
- → Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis(2014)245 cited
- → Azo-PROTAC: Novel Light-Controlled Small-Molecule Tool for Protein Knockdown(2020)162 cited
- → CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation(2019)137 cited
- → Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions(2016)117 cited
- → An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis(2016)113 cited
- → Structure–Activity and Structure–Property Relationship and Exploratory in Vivo Evaluation of the Nanomolar Keap1–Nrf2 Protein–Protein Interaction Inhibitor(2015)87 cited
- → Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency(2017)76 cited
- → A Weighted Discriminative Extreme Learning Machine Design for Lung Cancer Detection by an Electronic Nose System(2021)62 cited