Martha A. Ornelas
Publications by Year
Research Areas
Synthesis and Catalytic Reactions, Synthesis and Biological Evaluation, Epigenetics and DNA Methylation, Prostate Cancer Treatment and Research, Estrogen and related hormone effects
Most-Cited Works
- → C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase(2014)191 cited
- → Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor(2021)172 cited
- → Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer(2021)112 cited
- → Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants(2016)93 cited
- → Systematic Structure Modifications of Imidazo[1,2-a]pyrimidine to Reduce Metabolism Mediated by Aldehyde Oxidase (AO)(2011)80 cited
- → Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1(2020)77 cited
- → Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2 H )-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors(2016)68 cited
- → Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists(2011)67 cited
- → A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes(2014)53 cited
- → Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators(2013)46 cited