Sofia Karlström
Medivir (Sweden)(SE)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Catalytic Cross-Coupling Reactions, Crystallization and Solubility Studies
Most-Cited Works
- → Di-2-pyridylmethylamine-Based Palladium Complexes as New Catalysts for Heck, Suzuki, and Sonogashira Reactions in Organic and Aqueous Solvents(2003)289 cited
- → Suzuki–Miyaura and Related Cross‐Couplings in Aqueous Solvents Catalyzed by Di(2‐pyridyl)methylamine‐Palladium Dichloride Complexes(2004)138 cited
- → Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease(2012)136 cited
- → Di(2-pyridyl)methylamine–palladium dichloride complex covalently anchored to a styrene-maleic anhydride co-polymer as recoverable catalyst for C–C cross-coupling reactions in water(2005)127 cited
- → Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid Peptides(2012)99 cited
- → Substituted 7-Amino-5-thio-thiazolo[4,5-d]pyrimidines as Potent and Selective Antagonists of the Fractalkine Receptor (CX3CR1)(2013)70 cited
- → New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain(2012)65 cited
- → AZ-4217: A High Potency BACE Inhibitor Displaying Acute Central Efficacy in Different In Vivo Models and Reduced Amyloid Deposition in Tg2576 Mice(2013)39 cited
- → Discovery of USP7 small-molecule allosteric inhibitors(2020)11 cited
- → Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring(2013)5 cited