Howard E. Morton
AbbVie (United States)(US)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Synthetic Organic Chemistry Methods, Chemical Synthesis and Reactions, Chemical Synthesis and Analysis, Oxidative Organic Chemistry Reactions
Most-Cited Works
- → L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor(1989)328 cited
- → MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.(1990)316 cited
- → Development of a Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes for the Synthesis of Endothelin-A Antagonist ABT-546. Scope, Mechanism, and Further Application to the Synthesis of the Antidepressant Rolipram(2002)209 cited
- → Dimethylboron bromide and diphenylboron bromide: cleavage of acetals and ketals(1984)152 cited
- → Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes(1999)152 cited
- → Synthesis of α-amino and α-alkoxy aldehydes via oxoammonium oxidation(1992)121 cited
- → Preclinical development of an oral anti- Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis(2019)83 cited
- → Dimethylboron bromide and diphenylboron bromide. Acetal and ketal cleavage. Cleavage of MEM, MOM, and MTM ethers.(1983)83 cited
- → Reaction of (trimethylstanyl)copper(I) reagents with α,β-acettylenic esters(1989)82 cited
- → Stereoselective conjugate addition of lithium (phenylthio)(trimethylstannyl) cuprate to .alpha.,.beta.-acetylenic esters. Preparation of (E)- and (Z)-4-lithio-1,3-pentadienes and their reaction with electrophiles(1980)78 cited