Howard E. Morton

Publications by Year

Research Areas

Asymmetric Synthesis and Catalysis, Synthetic Organic Chemistry Methods, Chemical Synthesis and Reactions, Chemical Synthesis and Analysis, Oxidative Organic Chemistry Reactions

Most-Cited Works

• → L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor(1989)328 cited
• → MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.(1990)316 cited
• → Development of a Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes for the Synthesis of Endothelin-A Antagonist ABT-546. Scope, Mechanism, and Further Application to the Synthesis of the Antidepressant Rolipram(2002)209 cited
• → Dimethylboron bromide and diphenylboron bromide: cleavage of acetals and ketals(1984)152 cited
• → Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes(1999)152 cited
• → Synthesis of α-amino and α-alkoxy aldehydes via oxoammonium oxidation(1992)121 cited
• → Preclinical development of an oral anti- Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis(2019)83 cited
• → Dimethylboron bromide and diphenylboron bromide. Acetal and ketal cleavage. Cleavage of MEM, MOM, and MTM ethers.(1983)83 cited
• → Reaction of (trimethylstanyl)copper(I) reagents with α,β-acettylenic esters(1989)82 cited
• → Stereoselective conjugate addition of lithium (phenylthio)(trimethylstannyl) cuprate to .alpha.,.beta.-acetylenic esters. Preparation of (E)- and (Z)-4-lithio-1,3-pentadienes and their reaction with electrophiles(1980)78 cited