Emma F. Smith
University of Sheffield(GB)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Autophagy in Disease and Therapy, Genetic Neurodegenerative Diseases, Alzheimer's disease research and treatments
Most-Cited Works
- → The role of mitochondria in amyotrophic lateral sclerosis(2017)555 cited
- → The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy(2016)393 cited
- → SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits(2017)147 cited
- → Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?(2017)98 cited
- → C9orf72 plays a central role in Rab GTPase-dependent regulation of autophagy(2016)60 cited
- → An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD(2022)35 cited
- → Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation(2022)13 cited
- → C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons(2022)10 cited
- → C9orf72 -derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons(2021)
- → Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in C9orf72 Amyotrophic Lateral Sclerosis via ADA(2026)