Irina V. Lebedeva
Tri-Institutional Therapeutics Discovery Institute(US)
Publications by Year
Research Areas
Virus-based gene therapy research, CAR-T cell therapy research, Cancer Research and Treatments, Toxin Mechanisms and Immunotoxins, Cell death mechanisms and regulation
Most-Cited Works
- → mda- 7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK(2002)306 cited
- → Antisense Oligonucleotides: Promise and Reality(2001)240 cited
- → Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties(2001)219 cited
- → The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells(2002)209 cited
- → mda-7/IL-24: Multifunctional cancer-specific apoptosis-inducing cytokine(2006)178 cited
- Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity.(2000)
- → Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner(2003)169 cited
- → MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine(2002)157 cited
- → A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells(2001)154 cited
- → Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells(2005)145 cited